A mild and efficient one-step synthesis of quinolines.
نویسندگان
چکیده
[reaction: see text] The Friedländer synthesis of quinolines is an extensively employed protocol, yielding the desired heterocycle in a two-step reduction-condensation sequence. We have developed a mild, efficient, high-yielding single-step variant of this methodology, which employs SnCl(2) and ZnCl(2) to effect the reaction.
منابع مشابه
Natural kaolin as an efficient recyclable catalyst for the synthesis of new 2,4-disubstituted quinolines
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ورودعنوان ژورنال:
- Organic letters
دوره 5 23 شماره
صفحات -
تاریخ انتشار 2003